Modulation of raft domains in a lipid bilayer by boundary-active curcumin.

نویسندگان

  • Manami Tsukamoto
  • Kenichi Kuroda
  • Ayyalusamy Ramamoorthy
  • Kazuma Yasuhara
چکیده

The function and mode of action of curcumin in modulating the formation of lipid raft domains were investigated by microscopic observation using model membranes. Curcumin induces fusion of lipid raft domains at extremely low concentrations through the alteration of the boundary between the ordered and disordered phases.

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عنوان ژورنال:
  • Chemical communications

دوره 50 26  شماره 

صفحات  -

تاریخ انتشار 2014